Animal Experimentation

ECTS credits:
2,5 ECTS

Course parameters:
Language: English
Level of course: PhD course
Time of year: November 2016
No. of contact hours: 28 hours
Hours in total incl. preparation, assignment(s) 60 hours
Capacity limits: minimum 10, maximum 25 participants

Objectives of the course:
The aim of the course is to give the student knowledge on the use of animals for animal experimentation, and to provide the student with some practical experience in handling and use of experimental animals. Furthermore, to provide the PhD-student with the required skills and competences, which correspond to a category B course.

Learning outcomes and competences:
Having completed the course it is expected that the student has the following:

Knowledge:
The student knows:

  • The legal basis for animal experimentation
  • That experimentation with animals requires current training of the personal to secure the well-being of the animals and scientific outcome
  • The biological basis of animal experimentation

Skills and competences:
The student is able to:

  • Do handling and procedures in relevant animals used for experimentation
  • Explain basic principles on how to use animals for research
  • Apply principles of procedures on their future experiments
  • Reflect over the ethical basis for the use of animals for research

Compulsory programme:
Lectures and participation in discussion groups and exercises.

Course contents:
The course will cover the following elements:
Lectures covering the topics: Legislation and administration, laboratory animal facilities, ethics, human endpoints, anaesthesia and analgesia, health and hygiene, feeding and nutrition, handling and environment, breeding and reproduction, behavior and pain, planning of animal experiments, non-surgical and surgical procedures in experimental animals (rodents, poultry, pigs and cows), alternatives to animal experimentation and ethics.

The course is quality accredited by the Federation of European Laboratory Animal Science Associations (FELASA), and is based on the FELASA category B curriculum.

Prerequisites:
The students are expected to have basic knowledge in animal science including anatomy and physiology, animal genetics and animal nutrition

Name of lecturers:

  • Course responsible (temporary): Associate professor Ricarda Engberg (PhD, DVM)
  • Associate professor Frederik Dagnæs-Hansen, (PhD, DVM), Department of Biomedicine, Aarhus University
  • Section leader Charlotte Lauridsen (PhD, Cand.agro)
  • Senior Scientist Mette Herskin (PhD, Cand. Scient.)

Additional teachers to be announced

Type of course/teaching methods:
The course will be planned as a mixture of lectures, practical- and theoretical exercises

Literature:
To be announced (In English).

“Forsøgsdyrshåndbogen”: Håndbog for kategori B kursus. 3. Udgave. Red. Af Thomas C. Krohn. Institut for Veterinær Sygdomsbiologi, Det Biovidenskabelige Fakultet, Københavns Universitet.

Handbook of Laboratory Animal Management and Welfare, Sarah Wolfensohn and Maggie Lloyed, Wiley-Blackwell, 4. Edition, 2013.

Course homepage:
http://anis.au.dk/uddannelse/animal-experimentation/

Course assessment:
Individual presentation of key elements of animal experimentation. Exam will be performed immediately at the end of the course. The performance of the participants will be evaluated as passed/not passed

Provider:
Department of Animal Science, Aarhus University

Special comments on this course:
Capacity limit: Minimum 10, maximum 25.

Time:
7-10 November 2016 (4 days)

Place:
Aarhus University
Department of Animal Science
Blichers Allé 20, Tjele

Registration:
Deadline for registration is Thursday, 15 September 2016. Information regarding admission will be sent out no later than Saturday, 1 October 2016. Please pay registration fee 500 DKK (covers food, coffee, and materials).

For registration: Mette.GravesMadsen@anis.au.dk

If you have any questions, please contact Ricarda Engberg, e-mail Ricarda.Engberg@anis.au.dk

Animal Experimentation: course plan 2016

Date

Time

Lecture/practical

DAY 1

 

 

7/11

9-9.20

Introduction, learning goals, and practical information

7/11

9.30-10.30

Legislation

7/11

10.45-12.15

Ethics, 3R, alternatives, human endpoints

7/11

12.15-13

Lunch

7/11

12.45-13.30

Breeding and reproduction of rodents

7/11

13.30-16.30

Practical at rodent facility ANIS

Handling, oral dosing, injection techniques (s.c., i.v. and i.p.), blood sampling, anesthesia and suture techniques euthanasia rodents

DAY 2

 

 

8/11

9-10


Breeding and reproduction of production animals (cattle, pigs, and poultry)

8/11

10.15-11.00

Evolution of nociception and pain (rodents and production animals)

8/11

11.15-12.45

Monitoring of disease, pain and health Evaluation of level of distress

8/11

12.45-13:30

Lunch

8/11

13:30-15:30

Anaesthesia and analgesia in experimental animals, methods of euthanasia
Sterile working and human safety

DAY 3

 

 

9/11

9.00-9.45

Behavior and welfare of experimental animals (normal, abnormal, stress…)

9/11

9.45-10.30

Environmental factors (Housing, enrichment, noise, light, temperature…)

9/11

10.30-11.15

Use and selection of animal models

9/11

11.15-12.00

Animal models 1: Pain

9/11

12-12.30

LUNCH

9/11

12.30-16.30

Practical: Blood sampling, oral dosing injection techniques, anaesthesia, intubation,  catheterization vena jugularis
Pigs(surgery room)
Cattle (Stable)
Poultry (D23)

DAY 4

 

 

10/11

9.00-9.45

Feeding and nutrition of rodents and production animals

10/11

9.45-10.45

Animal models 2: Digestive tract  (cannulation) and metabolism (multi-catheterization)

10/11

10.45-12.15

Handling and training of production animals

10/11

12.15-13

LUNCH

10/11

13-15

Group work on application for animal experiments

10/11

15-16

EXAM (in writing)

 

 

 

 

Comments on content: 
Revised 11.08.2016