Electrical Properties of DNA and Their Use in Biosensors for Cancer Biomarkers

PhD defence, Friday 19 May 2017. László Kékedy-Nagy

2017.05.19 | Steffi Hjerrild Iversen

László Kékedy-Nagy

During his PhD studies László Kékedy-Nagy has studied electrical properties of DNA by electrochemical techniques and has developed DNA-based electrochemical biosensors that rely on those properties. He showed that electron transfer reactions in DNA strongly depended on the DNA sequence composition, redox probes used in studies, and that the electrode polarization affected a sub-molecular structure of DNA duplexes.

Based on these findings, László Kékedy-Nagy has developed several label-free assays for detection of blood-circulating protein cancer biomarkers, which may improve the quality of point-of-care testing and general monitoring of cancer treatment efficiency.

The PhD degree was completed at the Interdisciplinary Nanoscience Center (iNANO), Science and Technology, Aarhus University.

This résumé was prepared by the PhD student.

Friday 19 May 2017 at 14.15
Building 1593, room 012, the Lecture Theatre, iNANO House, Gustav Wieds Vej 14, Aarhus University, 8000 Aarhus C.
Title of dissertation:
Electron Transfer in DNA Molecules and Across DNA Films: DNA Electronics and Biosensing
Contact information:
László Kékedy-Nagy, e-mail: laszlo@inano.au.dk, tel.: +45 8715 6735

Members of the assessment committee:

Professor of Chemistry, Vice-Principal Research Heinz-Bernhard Kraatz, Department of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, Canada
Professor of Chemistry, Director Robert J. Forster, National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Dublin, Ireland
Professor Troels Skrydstrup (chair), iNANO and Department of Chemistry, Aarhus University
Main supervisor:

Associate Professor Elena Ferapontova, iNANO, Aarhus University
The PhD dissertation will be defended in English

The defence is public.
The dissertation is available for reading at the Graduate Scholl of Science and Technology/GSST, Ny Munkegade 120, building 1520, rooms 128-134, 8000 Aarhus C.

PhD defence
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Revised 23.02.2018