Identification of novel biomarkers of rare circulating tumour cells

PhD defence, Friday 4 November 2016. Mathias Lindh Jørgensen

2016.11.04 | Steffi Hjerrild Iversen

Mathias Lindh Jørgensen

During his studies, Mathias Lindh Jørgensen researched tumour cells in blood from colon cancer patients. Genomics have allowed for detailed analysis of these rare cells, however, genomics cannot shed light on important aspects regarding aberrant post-translational modifications and the location of proteins. Mathias Lindh Jørgensen therefore used a proteomic platform based on antibodies to explore circulating tumour cells in order to discover new markers of cancer.
This research will hopefully contribute to the development of the so-called liquid biopsy where analysis of a simple blood sample potentially can reveal early stage cancer.

The PhD degree was completed at the Department of Engineering, Science and Technology, Aarhus University.

The PhD student prepared this summary.

Time: Friday 4 November 2016 at 13.00
Place: Building 1523, room 318, Ny Munkegade 120, Aarhus University, 8000 Aarhus C.
Title of dissertation:
Identification and exploration of biomarkers associated to circulating tumour cells by recombinant antibody technology
Contact information: Mathias Lindh Jørgensen, e-mail: mlindh@eng.au.dk, tel.: +4561730378
Members of the assessment committee:
Research Scientist Dr. Patrick Chames, Department of Paoli-Calmettes, CNRS, IN-SERM, CRCM, Aix Marseille Université, France
Group Leader/Associate Professor Kim Bak Jensen, BRIC - Biotech Research & Innovation Centre, University of Copenhagen
Associate Professor Luis Álvarez-Vallina, Department of Engineering, Aarhus University (chair)
Main supervisor:
Associate Professor Peter Kristensen, Department of Engineering, Aarhus University
Language: The PhD dissertation will be defended in English

The defence is public.
The dissertation is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1520, rooms 128-134, 8000 Aarhus C.

PhD defence
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Revised 20.11.2017