Imaging with a nanopipette - a new approach for mapping surface charge density

PhD defence, Friday, 6 May 2016. Lasse Hyldgaard Klausen

2016.05.06 | Rikke J. Ljungmann

Lasse Hyldgaard Klausen

Top: Simulation of the ionic current passing through a nanopipette. Bottom: Surface charge density map of a supported lipid bilayer.

Surface charges can be found at virtually any water submersed surface. The density of charges determines the electrostatic properties of a surface, and the spatial distribution is an important characteristic of nano- and micro-sized systems. However, these structures are smaller than the wavelength of visible light, and new methods are required to “see” them.

During his PhD studies, Lasse Hyldgaard Klausen worked on a new approach using a nanopipette to visualize surface charges. Lasse investigated the flow of ions through the very sharp pipette tip when it was positioned near a surface, and he developed a novel method capable of mapping surface charge density with high quantitative precision and nanoscale resolution.

The developed method is a new way of characterizing surfaces, which provides researchers with previously unobtainable information about the nanoscale structure and properties of water submersed surfaces.

The PhD degree was completed at the Interdisciplinary Nanoscience Center (iNANO), Science and Technology, Aarhus University.

This résumé was prepared by the PhD student.

Time: Friday, 6 May 2016 at 13.15
Place: Building 1523, room 318, the Lecture Theatre, Department of Physics and Astronomy, Ny Munkegade 120, Aarhus University, 8000 Aarhus C.
Title of dissertation: Surface Charge Density Mapping with a Scanning Ion Conductance Microscope
Contact information: Lasse Hyldgaard Klausen, e-mail:, tel.: +45 2062 7625
Members of the assessment committee:
Professor Haiwon Lee, Department of Chemistry, Hanyang University, Seoul, Korea
Professor Francesco Stellacci, Institute of Materials, EPFL, Lausanne, Switzerland
Associate Professor Trolle René Linderoth (chair), iNANO and Department of Physics and Astronomy, Aarhus University
Main supervisor:
Associate Professor Mingdong Dong, iNANO, Aarhus University
Professor Flemming Besenbacher, iNANO, Aarhus University
Language: The PhD dissertation will be defended in English

The defence is public.
The dissertation is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1520, rooms 128-134, 8000 Aarhus C.

PhD defence
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Revised 23.02.2018