Regulation of local protein expression in the central nervous system – towards an understanding of the molecular details underlying the myelination process

PhD defence, Monday 13 February 2017. Julie Torvund-Jensen.

2017.02.13 | Camilla Steen Møller

Julie Torvund-Jensen

During her PhD studies, Julie Torvund-Jensen has investigated the mechanisms that regulate the expression of Myelin Basic Protein, an essential component of functional myelin. Myelin is an insulating layer that promotes the survival of neurons and enables electrical signals to be propagated at high speed throughout the nervous system.

Julie Torvund-Jensen has identified new players in the complex regulation of myelination and demonstrated their role related to protein expression. Furthermore, stable transgenic zebrafish lines that will be highly useful for future studies within this field have been developed.

The work of Julie Torvund-Jensen has brought new insight into the myelination process. Such knowledge is essential for the elucidation of the mechanisms causing myelin-related diseases, such as multiple sclerosis.

The PhD degree was completed at the Department of Molecular Biology and Genetics, Science and Technology, Aarhus University.

This résumé was prepared by the PhD student.

Time: Monday 13 February 2017 at 13.30
Place: Building 1253, room 211, the Lakeside Lecture Theatres - Merete Barker Auditorium, Aarhus University, Bartholins Allé 3, 8000 Aarhus C
Title of dissertation: In vitro and in vivo studies of the regulation of Myelin Basic Protein translation in the CNS
Contact information: Julie Torvund-Jensen, e-mail: jtj@mbg.au.dk, tel.: +45 50 52 02 69
Members of the assessment committee:
Professor Bente Finsen, Finsen-gruppen, BRIDGE, Brain Research - Inter-Disciplinary Guided Excellence, University of Southern Denmark, Denmark
Associate professor Wia Baron, Department of Cell Biology, University Medical Center Groningen (UMCG), University of Groningen, the Netherlands
Associate professor Charlotte Rhode Knudsen (chair), Department of Molecular Biology and Genetics, Aarhus University, Denmark
Main supervisor:
Professor Claus Oxvig, Department of Molecular Biology and Genetics, Science and Technology, Aarhus University
Co-supervisor:
Associate professor Lisbeth S. Laursen, Department of Molecular Biology and Genetics, Science and Technology, Aarhus University
Language: The PhD dissertation will be defended in English

The defence is public.
The dissertation is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1520, rooms 128-134, 8000 Aarhus C.

PhD defence
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Revised 24.02.2017